Introduction

Acknowledgements

List of abbreviations

Companion website

Anatomical and functional organization

1 Development of the nervous system

2 Organization of the nervous system

3 Autonomic nervous system

4 Enteric nervous system

5 Meninges and cerebrospinal fluid

6 Blood supply to the central nervous system

7 Cranial nerves

8 Anatomy of the brainstem

9 Organization of the spinal cord

10 Organization of the cerebral cortex and thalamus

11 Hypothalamus

Cells and neurophysiology

12 Cells of the nervous system I: neurones

13 Cells of the nervous system II: neuroglial cells

14 Ion channels

15 Resting membrane and action potential

16 Neuromuscular junction and synapses

17 Nerve conduction and synaptic integration

18 Neurotransmitters, receptors and their pathways

19 Main CNS neurotransmitters and their function

20 Skeletal muscle structure

21 Skeletal muscle contraction

Sensory systems

22 Sensory systems: an overview

23 Sensory transduction

24 Visual system I: the eye and retina

25 Visual system II: the visual pathways and subcortical visual areas

26 Visual system III: visual cortical areas

27 Auditory system I: the ear and cochlea

28 Auditory system II: auditory pathways and language

29 Vestibular system

30 Olfaction and taste

31 Somatosensory system

32 Pain systems I: nociceptors and nociceptive pathways

33 Pain systems II: pharmacology and management

34 Association cortices: the posterior parietal and prefrontal cortex

Motor systems

35 Organization of the motor system

36 Muscle spindle and lower motor neurone

37 Spinal cord motor organization and locomotion

38 Cortical motor areas

39 Primary motor cortex

40 Basal ganglia: anatomy and physiology

41 Basal ganglia: diseases and their treatments

42 Cerebellum

Cognition and neural plasticity

43 Reticular formation and sleep

44 Limbic system and long-term potentiation

45 Memory

46 Emotion, motivation and drug addiction

47 Neural plasticity and neurotrophic factors I: the peripheral nervous system

48 Neural plasticity and neurotrophic factors II: the central nervous system

49 Techniques for studying the nervous system

Applied neurobiology: the principles of neurology and psychiatry

50 Approach to the patient with neurological problems

51 Examination of the nervous system

52 Investigation of the nervous system

53 Imaging of the central nervous system

54 Clinical disorders of the sensory systems

55 Clinical disorders of the motor systems

56 Eye movements

57 Neurochemical disorders I: affective disorders

58 Neurochemical disorders II: schizophrenia

59 Neurochemical disorders III: anxiety

60 Neurodegenerative disorders

61 Neurophysiological disorders: epilepsy

62 Neuroimmunological disorders

63 Neurogenetic disorders

64 Cerebrovascular disease

65 Neuroradiological anatomy

History of neuroscientific discoveries

66 Historical neuroscience discoveries

Self-assessment case studies

Case studies and questions

Answers

Index