CHAPTER 01 암에 대한 이해
제01절 종양과 암의 정의···············································································································3
제02절 암의 분류······························································································································4
1. 상피성 종양·································································································································· 5
2. 비상피성 종양····························································································································· 7
3. 장기별 암의 발생빈도·············································································································· 8
4. 암의 발생원인····························································································································· 8
제03절 분화도 및 등급···················································································································9
제04절 암의 병기결정·················································································································· 10
제05절 암의 병기결정에 사용되는 분류체계······································································· 10
1. TNM System··························································································································10
2. SEER Summary Staging·································································································12
3. The Ann Arbor Staging System with Cotswolds Modifications··············15
4. International Federation of Gynecology and Obstetrics······························16
5. Dukes’ Classification········································································································18
6. Classification of Melanoma··························································································19
7. Jewett-Whitmore Staging Classification······························································20
제06절 종양표지자······················································································································· 21
1. 종양표지자 검사의 의의········································································································21
2. 종양표지자의 종류··················································································································22
3. 종양표지자의 장기 특이성···································································································27
4. 종양표지자 수치의 생리적 변동 인자··············································································28
5. 암의 원발장기와 종양표지자의 조합················································································29
CHAPTER 02 암등록사업
제01절 암등록································································································································ 35
1. 도입 배경 및 필요성···············································································································35
2. 암등록의 종류···························································································································36
제02절 암등록사업의 역사········································································································· 38
1. 유럽과 미국의 암등록 역사··································································································38
2. 우리나라의 암등록 역사········································································································39
제03절 우리나라의 암등록사업································································································ 42
1. 목적과 법적 근거·····················································································································42
2. 운영 주체 및 역할···················································································································42
3. 암등록통계사업의 절차 ········································································································45
제04절 국가암등록통계시스템································································································· 47
1. 암등록 조사서···························································································································47
2. 국가암등록통계시스템···········································································································49
CHAPTER 03 일반적 암등록 지침(항목별)
제01절 암환자 색출 방법············································································································ 59
1. 암환자 색출을 위한 자료원··································································································59
2. 암환자 색출 시 검토해야 하는 한국표준질병사인분류··············································60
제02절 암등록 대상······················································································································ 62
1. 등록 대상과 비등록 대상······································································································62
2. 암등록 원칙································································································································62
제03절 암등록 항목······················································································································ 64
1. 암등록 시 기재 항목···············································································································64
제04절 다중원발암·····················································································································102
1. 다중원발암의 개요··············································································································· 102
2. IARC/IACR 규칙·················································································································· 103
3. 동일 장기군과 동일 조직소견군······················································································ 104
4. ICD-O-3의 조혈계 악성종양···························································································· 106
5. 조혈계 악성종양의 다중원발암 구분············································································· 107
제05절 뇌종양 등록····················································································································113
1. 뇌종양 등록 범위·················································································································· 113
2. WHO 분류 진단명 중 뇌종양 등록에 해당되는 암종·············································· 115
제06절 ICD-10과 ICD-O의 비교··························································································117
1. ICD-10과 ICD-O의 범주··································································································· 117
CHAPTER 04 암에 대한 임상지식
제01절 위암···································································································································123
1. 위의 구조와 기능·················································································································· 123
2. 분류 코드································································································································· 124
3. 역학 및 병인··························································································································· 125
4. 진단방법··································································································································· 127
5. 치료방법··································································································································· 129
6. 실무예제··································································································································· 132
제02절 대장암······························································································································135
1. 대장의 구조와 기능·············································································································· 135
2. 분류 코드································································································································· 136
3. 대장암의 정의························································································································ 137
4. 역학 및 병인··························································································································· 138
5. 진단방법··································································································································· 142
6. 치료방법··································································································································· 148
7. 직장암······································································································································· 150
8. 항암화학요법·························································································································· 151
9. 방사선 치료····························································································································· 153
10. 대장암의 예방법················································································································· 153
11. 대장암 관련 통계··············································································································· 155
12. 실무예제································································································································ 156
제03절 간암···································································································································158
1. 간의 구조와 기능·················································································································· 158
2. 분류 코드································································································································· 159
3. 간암의 정의 및 종류············································································································ 160
4. 역학 및 병인··························································································································· 161
5. 진단방법··································································································································· 164
6. 치료방법··································································································································· 164
7. 간암의 예방법························································································································ 168
8. 간암 관련 통계······················································································································ 170
9. 세계 현황································································································································· 171
10. 실무예제································································································································ 172
제04절 폐암···································································································································174
1. 폐의 구조와 기능·················································································································· 174
2. 분류 코드································································································································· 175
3. 폐암의 정의 및 종류············································································································ 176
4. 역학 및 병인··························································································································· 177
5. 진단방법··································································································································· 181
6. 치료방법··································································································································· 183
7. 예방방법··································································································································· 187
8. 폐암 관련 통계······················································································································ 188
9. 실무예제··································································································································· 189
제05절 유방암······························································································································191
1. 유방의 구조와 기능·············································································································· 191
2. 분류 코드································································································································· 191
3. 역학 및 병인··························································································································· 193
4. 진단방법··································································································································· 195
5. 치료방법··································································································································· 197
6. 실무예제··································································································································· 199
제06절 자궁경부암·····················································································································202
1. 자궁의 구조와 기능·············································································································· 202
2. 분류 코드································································································································· 202
3. 역학 및 병인··························································································································· 203
4. 진단방법··································································································································· 204
5. 치료방법··································································································································· 206
6. 실무예제··································································································································· 207
제07절 난소암······························································································································210
1. 난소의 구조와 기능·············································································································· 210
2. 분류 코드································································································································· 210
3. 역학 및 병인··························································································································· 211
4. 진단방법··································································································································· 212
5. 치료방법··································································································································· 214
6. 실무예제··································································································································· 215
제08절 방광암······························································································································218
1. 방광의 위치와 기능·············································································································· 218
2. 분류 코드································································································································· 218
3. 역학 및 병인··························································································································· 219
4. 진단방법··································································································································· 221
5. 치료방법··································································································································· 222
6. 실무예제··································································································································· 225
제09절 전립샘암··························································································································227
1. 전립샘의 구조와 기능········································································································· 227
2. 분류 코드································································································································· 227
3. 역학 및 병인··························································································································· 228
4. 진단방법··································································································································· 231
5. 치료방법··································································································································· 233
6. 실무예제··································································································································· 235
제10절 혈액암(백혈병, 림프종, 골수종)··············································································238
급성 골수성 백혈병···················································································································· 239
급성 림프구성 백혈병·············································································································· 242
만성 골수성 백혈병··················································································································· 244
다발성 골수종····························································································································· 247
제11절 악성림프종·····················································································································251
1. 림프절의 위치 및 기능········································································································ 251
2. 분류 코드································································································································· 252
3. 역학 및 병인··························································································································· 252
4. 진단방법··································································································································· 255
5. 치료방법··································································································································· 255
6. 실무예제··································································································································· 256
CHAPTER 05 암등록 자료의 질 관리와 통계
제01절 암등록 자료····················································································································261
제02절 완벽성······························································································································262
1. 자료 소스································································································································· 262
2. 사망 : 발생비························································································································· 264
3. 역사적 자료 방법·················································································································· 265
제03절 타당성······························································································································265
1. 진단 기준 방법······················································································································ 266
2. 결측 정보································································································································· 268
3. 재발췌 및 재코딩·················································································································· 271
4. 내적 일관성 방법·················································································································· 271
제04절 한국 중앙암등록본부 질 관리··················································································276
1. 프로그램 설명························································································································ 276
2. 자료정리 주의 사항·············································································································· 279
제05절 암등록 통계····················································································································295
1. 암통계 관련 용어 정의········································································································ 295
2. 암발생률··································································································································· 298
3. 암사망률··································································································································· 299
4. 암생존율··································································································································· 299
5. 암유병자수······························································································································ 299
부 록··························································································································301
찾아보기··························································································································313