Section One - Tumour

1 - Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

2 - MGMT gene silencing and benefit from temozolomide in glioblastoma

3 - Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial

4 - A randomized trial of surgery in the treatment of single metastases to the brain

5 - Prognostic factors for survival in adult patients with cerebral low-grade glioma

6 - Long-term outcomes after supratotal resection of diffuse low-grade gliomas: a consecutive series with 11-year follow-up

7 - The recurrence of intracranial meningiomas after surgical treatment

8 - Phase I/II study of resection and intraoperative cesium-131 radioisotope brachytherapy in patients with newly diagnosed brain metastases

9 - Natural history of asymptomatic colloid cysts of the third ventricle

Section Two - Vascular

10 - Surgical Risk as Related to Time of Intervention in the Repair of Intracranial Aneurysms

11 - International Subarachnoid Aneurysm Trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised trial

12 - International Study of Unruptured Intracranial Aneurysms Investigators. (ISUIA2) Unruptured intracranial aneurysms: natural history, clinical outcome, and risks of surgical and endovascular treatment.

13 - Effect of oral nimodipine on cerebral infarction and outcome after subarachnoid haemorrhage: British aneurysm nimodipine trial

14 - A proposed grading system for arteriovenous malformations

15 - Early decompressive surgery in malignant infarction of the middle cerebral artery: a pooled analysis of three randomised controlled trials

16 - Benefit of Carotid Endarterectomy in Patients with Symptomatic Moderate or Severe Stenosis. North American Symptomatic Carotid Endarterectomy Trial (NASCET)

17 - Trial of Early Minimally Invasive Removal of Intracerebral Hemorrhage (ENRICH)

Section Three - Paediatrics18 - Randomized trial of cerebrospinal fluid shunt valve design in pediatric hydrocephalus.

19 - Endoscopic third ventriculostomy in the treatment of childhood hydrocephalus

20 - Antibiotic or silver versus standard ventriculoperitoneal shunts (BASICS): a multicentre, single-blinded, randomised trial and economic evaluation

21 - A Randomized Trial of Prenatal versus Postnatal Repair of Myelomeningocele (MOMS trial)

22 - Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants less than 1,500 gm.

23 - Intrinsic brain-stem tumors of childhood: surgical indications

24 - Molecular subgroups of medulloblastoma: the current consensus

25 - Pial Synangiosis for Moyamoya Syndrome in Children

26 - Hypothermia Therapy after Traumatic Brain Injury in Children

Section Four - Functional/Epilepsy

27 - The first clinical trial to establish deep brain stimulation of the subthalamic nucleus as an evidence-based treatment for Parkinson’s disease

28 - The Long-term Outcome of Microvascular Decompression for Trigeminal Neuralgia

29 - A Randomized, Controlled Trial of Surgery for Temporal-Lobe Epilepsy

30 - Early Identification of Refractory Epilepsy

31 - Vagus nerve stimulation for treatment of partial seizures:
1. A controlled study of effect on seizures

32 - Intracarotid injection of sodium amytal for the lateralization of cerebral speech dominance

Section Five - Head Trauma

33 - Assessment of coma and impaired consciousness. A practical scale

34 - Traumatic Acute Subdural Hematoma: Major Mortality Reduction in Comatose Patients Treated within Four Hours

35 - Use of drains versus no drains after burr-hole evacuation of chronic subdural haematoma: a randomised controlled trial

36 - Significance of intracranial hypertension in severe head injury

37 - A randomized, double-blind study of phenytoin for the prevention of post-traumatic seizures

38 - Final results of MRC CRASH, a randomised placebo-controlled trial of intravenous corticosteroid in adults with head injury-outcomes at 6 months.

39 - Trial of Decompressive Craniectomy for Traumatic Intracranial Hypertension (RESCUEicp trial).

40 - Surgical Management of Acute Epidural Hematomas

Section Six - Spine Trauma

41 - Validity of a Set of Clinical Criteria to Rule Out Injury to the Cervical Spine in Patients with Blunt Trauma

42 - The subaxial cervical spine injury classification system: a novel approach to recognize the importance of morphology, neurology, and integrity of the disco-ligamentous complex

43 - A new classification of thoracolumbar injuries: the importance of injury morphology, the integrity of the posterior ligamentous complex, and neurologic status

44 - A Clinical Practice Guideline for the Management of Patients With Acute Spinal Cord Injury: Recommendations on the Use of Methylprednisolone Sodium Succinate

Section Seven - Spine

45 - Effect of High-dose Dexamethasone in Carcinomatous Metastatic Spinal Cord Compression Treated with Radiotherapy: a Randomised Trial

46 - Direct Decompressive Surgical Resection in the Treatment of Spinal Cord Compression Caused by Metastatic Cancer: A Randomised Trial

47 - Surgical vs nonoperative treatment for lumbar disc herniation: the Spine Patient Outcomes Research Trial (SPORT): a randomized trial

48 - Cauda Equina Syndrome Secondary to Lumbar Disc Herniation: A Meta-Analysis of Surgical Outcomes

49 - Surgical vs nonsurgical therapy for lumbar spinal stenosis

50 - The anterior approach for removal of ruptured cervical disks