I: Introduction; 1: Governing Global Health in the Twenty-First Century; II: Global Challenges and Responses; 2: The Transformation in Global Health Collaboration since the 1990s; 3: Global Health, Social Movements, and Governance; 4: A Pathology of Public Health Securitism: Approaching Pandemics as Security Threats; III: The Central Institutions: The Multilateral System; 5: Public Health in a Globalising World: The Perspective from the World Health Organization; 6: Reaching the Millennium Development Goals; 7: Can the World Trade Organization Help Achieve the Health Millennium Development Goals?; 8: Partnerships for Health, the Environment, and Governance; IV: The Central Institutions: The G8 System; 9: The G8 and Global Health Governance; 10: Diplomatic Rhetoric or Rhetorical Diplomacy: The G8 and Global Health Governance; 11: Keeping Faith with Africa's Health: Catalysing G8 Compliance; 12: Breaking Faith with Africa: The G8 and Population Health after Gleneagles; 13: Global Health and Universal Human Rights: The Case for G8 Accountability; V: Conclusion; 14: Toward Innovation in Global Health Governance