Contents: Preface. Part I: Neuropsychological Aspects of Chronic Illnesses.M.A. Pappolla, N.K. Robakis, Neuropathology and Molecular Biology of Alzheimer's Disease. D.J. Johannessen, R.C. Mohs, B.A. Lawlor, L.D. Altstiel, Early Markers of Disease Expression in Alzheimer's Disease. B.A. Lawlor, Experimental Therapeutics of Alzheimer's Disease. J.R. Hesselink, T.L. Jernigan, W.C. Heindel, Structural Brain Imaging of HIV Infection. R.K. Heaton, R.A. Velin, J.H. Atkinson, S.J. Gulevich, J.A. McCutchan, J.R. Hesselink, J.L. Chandler, I. Grant, HNRC Group, Neuropsychological Impairment in an HIV-Positive Male Cohort. Part II: Stress and Psychosocial Aspects of Chronic Illnesses.L.A. Rosenblum, M. Andrews, Primate Developmental Models of Stress. S. Folkman, M. Chesney, Coping with HIV Infection. M.H. Antoni, B.A. Esterling, S. Lutgendorf, M.A. Fletcher, N. Schneiderman, Psychosocial Stressors, Herpes Virus Reactivation and HIV-1 Infection. A.B. Zonderman, Symptoms of Depression Are Not a Risk for Cancer Morbidity and Mortality. B.H. Fox, A Hypothesis to Reconcile Conflicting Conclusions in Studies Relating Depressed Mood to Later Cancer. D. Spiegel, Psychosocial Influences on Cancer Survival. Part III: Human Sexuality and Disease.R.C. Schiavi, Introduction: Research in Sexuality and AIDS. J.M. Reinisch, S.A. Sanders, M. Ziemba-Davis, Self-Labeled Sexual Orientation and Sexual Behavior: Considerations for STD-Related Biomedical Research and Education. V.M. Mays, S.D. Cochran, HIV/AIDS in the African-American Community: Changing Concerns, Changing Behaviors. Part IV: Psychoneuroimmunology and Chronic Illnesses.S. Perry, Psychoneuroimmunology and AIDS: Challenge or "Challenger?" M. Stein, A.H. Miller, Future Directions for Psychoneuroimmunology Research.