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Contents Preface................................................................................................................................................................ix Editor..................................................................................................................................................................xi Contributors.................................................................................................................................................... xiii Chapter 1 Principles behind Radiopharmacy.................................................................................................1 Thuy A. Tran and Erik Samen Chapter 2 Radiopharmaceuticals for Diagnostics: Planar/ SPECT..............................................................13 Jim Ballinger and Jacek Koziorowski Chapter 3 Radiopharmaceuticals for Diagnostics: PET...............................................................................27 Philip H. Elsinga Chapter 4 Radiopharmaceuticals for Radionuclide Therapy.......................................................................39 Meltem Ocak, Emre Demirci, Jessie R. Nedrow and Rebecca Krimins Chapter 5 Design Considerations for a Radiopharmaceutical Production Facility.....................................55 Nic Gillings Chapter 6 Methods and Equipment for Quality Control of Radiopharmaceuticals.....................................59 Rolf Zijlma, Danique Giesen, Yvette Kruiter, Philip H. Elsinga and Gert Luurtsema Chapter 7 Environmental Compliance and Control for Radiopharmaceutical Production: Commercial Manufacturing and Extemporaneous Preparation......................................................................................71 Ching-?Hung Chiu, Ya-?Yao Huang, Wen-?Yi Chang and Jacek Koziorowski Chapter 8 GMP ? Rules and Recommendations..........................................................................................87 Oliver Neels Chapter 9 Management of Radioactive Waste in Nuclear Medicine...........................................................95 Lena Jonsson and Hanna Holstein Chapter 10 Translation of Radiopharmaceuticals: Mouse to Man..............................................................101 Pedro Fragoso Costa, Latifa Rbah-?Vidal, An Aerts, Fijs W.B. van Leeuwen and Margret Schottelius Chapter 11 Radionuclide Bone Scintigraphy...............................................................................................117 Kanhaiyalal Agrawal and Gopinath Gnanasegaran vi Chapter 12 Radionuclide Examination of the Kidneys................................................................................139 Martin ?amal and Ji?i Trnka Chapter 13 Neuroimaging in Nuclear Medicine..........................................................................................173 Anne Larsson Stromvall and Susanna Jakobson Mo Chapter 14 Methodology and Clinical Implementation of Ventilation/ Perfusion Tomography for Diagnosis and Follow- up of Pulmonary Embolism and Other Pulmonary Diseases ? Clinical Use of Hybrid V/ P SPECT- CT.............................................................................................................189 Marika Bajc and Ari Lindqvist Chapter 15 Myocardial Perfusion Imaging..................................................................................................201 Elin Tragardh, David Minarik and Mark Lubberink Chapter 16 Infection and Inflammation.......................................................................................................213 Erik H.J.G. Aarntzen and Andor W.J.M. Glaudemans Chapter 17 Special Considerations in Pediatric Nuclear Medicine.............................................................231 Sofie Lindskov Hansen, Soren Holm, Liselotte Hojgaard and Lise Borgwardt Chapter 18 Antibody- based Radionuclide Imaging.....................................................................................243 Steffie M.B. Peters, Erik H.J.G. Aarntzen and Sandra Heskamp Chapter 19 Radionuclide- based Diagnosis and Therapy of Prostate Cancer...............................................255 Sven-?Erik Strand, Mohamed Altai, Joanna Strand and David Ulmert Chapter 20 Peptide Receptor Radionuclide Therapy for Neuroendocrine Tumours...................................305 Anna Sundlov and Katarina Sjogreen Gleisner Chapter 21 Lymphoscintigraphy.................................................................................................................313 Rimma Axelsson, Maria Holstensson and Ulrika Estenberg Chapter 22 Diagnostic Ultrasound..............................................................................................................325 Tomas Jansson Chapter 23 Clinical Trials ? Purpose and Procedures................................................................................337 Anna Sundlov |