Foreword by Chand Khanna, Ethos Veterinary. The Contribution of Pets to Human and Veterinary Medicine. Companion Animals Models of Human Disease. Specific Diseases of Large Animals and Man. Cancer Research is Leading the Way. Investment Dynamics in the World of Pharma. How to Perform Research in Spontaneous Models of Disease. The Use of Animals in Research. DNA Methods in Veterinary Medicine. The Importance of Collecting Tissue from Pets. The FDA New Animal Drug Approval Process. Clinical Trials, Patient Recruitment and Advertising. One Health: Animals, Humans and Our Planet. Communications and Expectations. Ethical Considerations. Appendix A: Funding for Veterinary Clinical Research. Appendix B: Resources for Veterinary Clinical Research (also available as online Download).